Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 6/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.35 |
| ▸ | RAF1 | P04049 | 3/20 | 0.33 |
| ▸ | BRAF | P15056 | 3/20 | 0.33 |
| ▸ | VNN1 | O95497 | 2/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | LIPC | P11150 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765285 | 1.00 | GLRA1 (0.39) | GLRA1PDE2ALIPGRAF1BRAF | |
| SCHEMBL30765202 | 1.00 | GLRA1 (0.39) | GLRA1PDE2ALIPGRAF1BRAF | |
| SCHEMBL27263346 | 0.91 | NPC1 (0.43) | NAMPTNPC1 | |
| SCHEMBL30765379 | 0.91 | NPC1 (0.43) | NAMPTNPC1 | |
| SCHEMBL27263347 | 0.91 | NPC1 (0.43) | NAMPTNPC1 | |
| SCHEMBL30765178 | 0.91 | NPC1 (0.43) | NAMPTNPC1 | |
| SCHEMBL27262365 | 0.89 | TGFBR1 (0.42) | RAF1BRAFTGFBR1 | |
| SCHEMBL30765407 | 0.89 | TGFBR1 (0.42) | RAF1BRAFTGFBR1 | |
| SCHEMBL32672619 | 0.89 | GLRA1 (0.38) | GLRA1PDE2ALIPGVNN1NAMPT | |
| SCHEMBL32672561 | 0.89 | GLRA1 (0.38) | GLRA1PDE2ALIPGVNN1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024033280-A1 | FUROPYRIDIN AND FUROPYRIMIDIN, INHIBITORS OF PI4K, FOR USE IN THE TREATMENT OF PARASITE INFECTION AND MALARIA | MERCK PATENT GMBH (DE) | 2024-02-15 | — | — | WO | disclosed |