Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15551701 | 1.00 | L3MBTL1 (0.55) | L3MBTL1KDM4ETSHRRECQLHPGD | |
| SCHEMBL13336459 | 0.90 | HPGD (0.51) | L3MBTL1HPGDRAB9AMEN1KMT2A | |
| SCHEMBL16687456 | 0.90 | HPGD (0.55) | L3MBTL1TSHRHPGDRAB9AMEN1 | |
| SCHEMBL18274825 | 0.88 | HPGD (0.56) | TSHRHPGDRAB9AMEN1KMT2A | |
| SCHEMBL15551438 | 0.88 | HPGD (0.56) | TSHRHPGDRAB9AMEN1KMT2A | |
| SCHEMBL29709543 | 0.87 | HPGD (0.49) | L3MBTL1TSHRHPGDMEN1KMT2A | |
| SCHEMBL585882 | 0.87 | HPGD (0.49) | L3MBTL1TSHRHPGDMEN1KMT2A | |
| SCHEMBL15538911 | 0.86 | HPGD (0.46) | L3MBTL1KDM4ETSHRRECQLHPGD | |
| SCHEMBL20033488 | 0.85 | L3MBTL1 (0.51) | L3MBTL1KDM4ETSHRRECQLHPGD | |
| SCHEMBL15549744 | 0.85 | ACHE (0.55) | L3MBTL1TSHRHPGDRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4619397-A1 | SALT-INDUCIBLE KINASES (SIK) INHIBITORS AND METHODS OF USES THEREOF | Insilico Medicine IP Limited (HK) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024104441-A1 | SALT-INDUCIBLE KINASES (SIK) INHIBITORS AND METHODS OF USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2024-05-23 | — | — | WO | disclosed |
| WO-2024033280-A1 | FUROPYRIDIN AND FUROPYRIMIDIN, INHIBITORS OF PI4K, FOR USE IN THE TREATMENT OF PARASITE INFECTION AND MALARIA | MERCK PATENT GMBH (DE) | 2024-02-15 | — | — | WO | disclosed |