Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 11/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ASPH | Q12797 | 2/20 | 0.39 |
| ▸ | RIOX2 | Q8IUF8 | 2/20 | 0.39 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31558528 | 0.93 | BCHE (0.40) | BCHEKDM4EASPHRIOX2KDM8 | |
| SCHEMBL30765950 | 0.90 | BCHE (0.38) | BCHEKDM4EASPHRIOX2KDM8 | |
| SCHEMBL30765744 | 0.89 | BCHE (0.38) | BCHEKDM4EASPHRIOX2KDM8 | |
| SCHEMBL30765978 | 0.87 | ELANE (0.41) | BCHEKDM4EASPHRIOX2KDM8 | |
| SCHEMBL30765946 | 0.82 | F2 (0.39) | BCHEKDM6BKDM4CF2PRSS1 | |
| SCHEMBL30765687 | 0.79 | BCHE (0.41) | BCHEKDM4EASPHRIOX2KDM8 | |
| SCHEMBL30765476 | 0.79 | ELANE (0.40) | BCHEKDM4EF2 | |
| SCHEMBL30765659 | 0.73 | ELANE (0.39) | KDM4EASPHRIOX2KDM8EGLN1 | |
| SCHEMBL30766097 | 0.73 | ASPH (0.49) | KDM4EASPHRIOX2KDM8EGLN1 | |
| SCHEMBL30765706 | 0.70 | ELANE (0.47) | KDM4EEGLN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| CN-119768164-A | Pharmaceutical compounds for treating complement-mediated disorders | 阿雷克森制药公司 | 2025-04-04 | — | — | CN | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |