SCHEMBL30765664

SCHEMBL30765664

COC(=O)Cn1c(-c2ccccc2)ncc(NCCCO[C@@H]2CO[C@H]3[C@@H]2OC[C@H]3OCc2ccccc2)c1=O

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.44
ELANE P08246 12/20 0.43
KLK7 P49862 7/20 0.41
KLK5 Q9Y337 5/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30765517 0.91 ELANE (0.40) BCHEELANE
SCHEMBL30765857 0.83 BCHE (0.41) BCHEELANE
SCHEMBL30765638 0.83 GAA (0.41) BCHEELANEKLK7KLK5
SCHEMBL30766052 0.82 KLK7 (0.42) BCHEELANEKLK7KLK5
SCHEMBL30765726 0.81 BCHE (0.44) BCHEELANE
SCHEMBL30765813 0.80 ELANE (0.42) BCHEELANEKLK7KLK5
SCHEMBL30765978 0.76 ELANE (0.41) BCHEELANE
SCHEMBL30765476 0.75 ELANE (0.40) BCHEELANEKLK7KLK5
SCHEMBL30765994 0.72 ELANE (0.46) ELANE
SCHEMBL30766097 0.71 ASPH (0.49) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4568666-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS Alexion Pharmaceuticals, Inc. (US) 2025-06-18 EP disclosed
WO-2024035686-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ALEXION PHARMACEUTICALS, INC. (US) 2024-02-15 WO disclosed