Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765989 | 0.85 | KDM4E (0.51) | KDM4EHSD17B10HPGDALDH1A1L3MBTL1 | |
| SCHEMBL6239360 | 0.84 | CMA1 (0.53) | KDM4EHSD17B10ELANE | |
| Hydrochloric Acid SCHEMBL6805327 | 0.82 | CMA1 (0.53) | KDM4EHSD17B10ELANE | |
| SCHEMBL6804111 | 0.82 | CMA1 (0.53) | KDM4EHSD17B10ELANE | |
| SCHEMBL6241617 | 0.79 | KDM4E (0.44) | KDM4EHSD17B10HPGDALDH1A1APEX1 | |
| SCHEMBL7965688 | 0.79 | KDM4E (0.45) | KDM4EHSD17B10HPGDALDH1A1L3MBTL1 | |
| SCHEMBL6259007 | 0.78 | ELANE (0.47) | KDM4EHSD17B10HPGDALDH1A1APEX1 | |
| SCHEMBL5728202 | 0.78 | ELANE (0.54) | KDM4EHSD17B10HPGDELANE | |
| SCHEMBL30765762 | 0.77 | ALDH1A1 (0.42) | KDM4EHSD17B10HPGDALDH1A1ALOX15 | |
| SCHEMBL6240894 | 0.77 | ELANE (0.51) | KDM4EHSD17B10HPGDALDH1A1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| CN-119768164-A | Pharmaceutical compounds for treating complement-mediated disorders | 阿雷克森制药公司 | 2025-04-04 | — | — | CN | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |