Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SLC27A1 | Q6PCB7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765674 | 0.89 | ALDH1A1 (0.42) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30765677 | 0.77 | KDM4E (0.49) | ALDH1A1GLAKDM4EHPGDALOX15 | |
| SCHEMBL31558529 | 0.71 | F10 (0.34) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17332419 | 0.69 | NPC1 (0.51) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6239360 | 0.69 | CMA1 (0.53) | KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL6805327 | 0.68 | CMA1 (0.53) | KDM4EHSD17B10 | |
| SCHEMBL6804111 | 0.68 | CMA1 (0.53) | KDM4EHSD17B10 | |
| SCHEMBL30765587 | 0.66 | KDM4E (0.42) | ALDH1A1KDM4EHPGDALOX15KMT2A | |
| SCHEMBL7965688 | 0.65 | KDM4E (0.45) | ALDH1A1SMN1; SMN2KDM4EGAAHPGD | |
| SCHEMBL6241617 | 0.65 | KDM4E (0.44) | ALDH1A1LMNARAB9AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| CN-119768164-A | Pharmaceutical compounds for treating complement-mediated disorders | 阿雷克森制药公司 | 2025-04-04 | — | — | CN | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |