Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | CTRC | Q99895 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7951054 | 0.89 | CYP1A2 (0.43) | KDM4EHPGDHSD17B10CYP1A2CYP2C9 | |
| SCHEMBL7965013 | 0.82 | HSD17B10 (0.37) | KDM4EHPGDHSD17B10CYP1A2CYP2C9 | |
| SCHEMBL7962214 | 0.81 | ALDH1A1 (0.46) | KDM4EHPGDHSD17B10CYP1A2CYP2C19 | |
| SCHEMBL7965891 | 0.80 | KCNA5 (0.41) | KDM4EHSD17B10ALDH1A1SMN1; SMN2ELANE | |
| SCHEMBL30765677 | 0.79 | KDM4E (0.49) | KDM4EHPGDHSD17B10CYP1A2CYP2C9 | |
| SCHEMBL6239360 | 0.78 | CMA1 (0.53) | KDM4EHSD17B10ELANECMA1CTRC | |
| SCHEMBL7960592 | 0.77 | SMN1; SMN2 (0.60) | KDM4EHPGDHSD17B10CYP1A2CYP2C9 | |
| SCHEMBL6804111 | 0.77 | CMA1 (0.53) | KDM4EHSD17B10ELANECMA1CTRC | |
| Hydrochloric Acid SCHEMBL6805327 | 0.77 | CMA1 (0.53) | KDM4EHSD17B10ELANECMA1CTRC | |
| SCHEMBL5728202 | 0.75 | ELANE (0.54) | KDM4EHPGDHSD17B10ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300337-B1 | Acetamide derivative and use thereof | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-1055683-A1 | NOVEL ACETAMIDE DERIVATIVE AND USE THEREOF | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-11-29 | — | — | EP | disclosed |