Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765947 | 0.88 | LMNA (0.40) | ALDH1A1KDM4ELMNANPSR1RXFP1 | |
| SCHEMBL30765891 | 0.86 | GAA (0.40) | ALDH1A1KDM4ELMNANPSR1MAPT | |
| SCHEMBL30765931 | 0.85 | ALDH1A1 (0.37) | ALDH1A1KDM4ELMNAJAK2JAK1 | |
| SCHEMBL30765941 | 0.85 | ALDH1A1 (0.37) | ALDH1A1KDM4ELMNAJAK2JAK1 | |
| SCHEMBL30765777 | 0.84 | HCRTR1 (0.40) | ALDH1A1KDM4ELMNAJAK2JAK1 | |
| SCHEMBL30765836 | 0.83 | KDM4E (0.36) | ALDH1A1KDM4ELMNAJAK2JAK1 | |
| SCHEMBL30765833 | 0.83 | JAK2 (0.38) | ALDH1A1KDM4ELMNAJAK2JAK1 | |
| SCHEMBL30765944 | 0.81 | ALDH1A1 (0.37) | ALDH1A1KDM4ELMNAJAK2JAK1 | |
| SCHEMBL30765948 | 0.81 | LMNA (0.39) | LMNANPSR1RXFP1 | |
| SCHEMBL30765939 | 0.81 | LMNA (0.35) | ALDH1A1KDM4ELMNAJAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |