Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765737 | 0.87 | LMNA (0.37) | LMNAUSP2ALDH1A1MAPTKDM4E | |
| SCHEMBL30765588 | 0.86 | MEN1 (0.42) | LMNAALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL30765957 | 0.83 | ALDH1A1 (0.38) | LMNAUSP2JAK2JAK1JAK3 | |
| SCHEMBL30765941 | 0.82 | ALDH1A1 (0.37) | LMNAUSP2JAK2JAK1JAK3 | |
| SCHEMBL30765931 | 0.82 | ALDH1A1 (0.37) | LMNAUSP2JAK2JAK1JAK3 | |
| SCHEMBL30765991 | 0.82 | ELANE (0.42) | LMNAJAK2JAK1JAK3ALDH1A1 | |
| SCHEMBL30765995 | 0.82 | ALDH1A1 (0.37) | LMNAUSP2JAK2JAK1JAK3 | |
| SCHEMBL30766046 | 0.81 | JAK2 (0.37) | LMNAUSP2JAK2JAK1JAK3 | |
| SCHEMBL30766002 | 0.80 | USP2 (0.37) | LMNAUSP2JAK2JAK1JAK3 | |
| SCHEMBL30765797 | 0.80 | KMT2A (0.40) | LMNAUSP2ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |