Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765867 | 0.88 | HDAC6 (0.44) | KMT2APOLBRXFP1MAPTLMNA | |
| SCHEMBL30765801 | 0.86 | LMNA (0.41) | KMT2APOLBRXFP1MAPTLMNA | |
| SCHEMBL30765957 | 0.84 | ALDH1A1 (0.38) | KMT2APOLBRXFP1MAPTLMNA | |
| SCHEMBL30765995 | 0.83 | ALDH1A1 (0.37) | KMT2ARXFP1MAPTLMNAKDM4E | |
| SCHEMBL30765991 | 0.83 | ELANE (0.42) | LMNAKDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL30765931 | 0.83 | ALDH1A1 (0.37) | KMT2ARXFP1MAPTLMNAKDM4E | |
| SCHEMBL30765941 | 0.83 | ALDH1A1 (0.37) | KMT2ARXFP1MAPTLMNAKDM4E | |
| SCHEMBL30766046 | 0.82 | JAK2 (0.37) | KMT2ARXFP1MAPTLMNARAB9A | |
| SCHEMBL30765521 | 0.81 | KMT2A (0.38) | KMT2APOLBRXFP1MAPTLMNA | |
| SCHEMBL30765733 | 0.81 | KMT2A (0.36) | KMT2APOLBRXFP1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |