Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PDE9A | O76083 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765600 | 0.92 | KDM4C (0.44) | MAPTKDM4CALDH1A1TSHRNPSR1 | |
| SCHEMBL30765933 | 0.89 | KDM4C (0.45) | MAPTKDM4CALDH1A1TSHRNPSR1 | |
| SCHEMBL30765668 | 0.79 | GAA (0.50) | MAPTKDM4CALDH1A1TSHRNPSR1 | |
| SCHEMBL30765741 | 0.77 | LMNA (0.41) | MAPTALDH1A1POLBTDP1LMNA | |
| SCHEMBL30765482 | 0.75 | KDM4C (0.50) | MAPTKDM4CALDH1A1TSHRNPSR1 | |
| SCHEMBL30765526 | 0.75 | KDM4C (0.46) | MAPTKDM4CALDH1A1TSHRNPSR1 | |
| SCHEMBL30765999 | 0.75 | PDE4B (0.44) | MAPTKDM4CALDH1A1TSHRNPSR1 | |
| SCHEMBL31558534 | 0.74 | KDM4C (0.48) | MAPTKDM4CALDH1A1TSHRNPSR1 | |
| SCHEMBL30766080 | 0.71 | MEN1 (0.45) | MAPTALDH1A1TSHRNPSR1TP53 | |
| SCHEMBL16993397 | 0.69 | MAPT (0.65) | MAPTKDM4CALDH1A1TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |