Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | TPH1 | P17752 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765600 | 0.85 | KDM4C (0.44) | LMNATDP1ALDH1A1MAPTMEN1 | |
| SCHEMBL30765891 | 0.84 | GAA (0.40) | LMNATDP1KDM4EALDH1A1MAPT | |
| SCHEMBL30765606 | 0.78 | MEN1 (0.44) | LMNAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL30765723 | 0.77 | MAPT (0.47) | LMNATDP1ALDH1A1MAPTHPGD | |
| SCHEMBL30766080 | 0.77 | MEN1 (0.45) | LMNAKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL30765661 | 0.74 | MEN1 (0.48) | LMNAKDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL30765833 | 0.72 | JAK2 (0.38) | LMNAKDM4EALDH1A1SMN1; SMN2POLB | |
| SCHEMBL30765933 | 0.71 | KDM4C (0.45) | LMNAKDM4EALDH1A1MAPT | |
| SCHEMBL30765472 | 0.71 | MEN1 (0.42) | LMNAKDM4EMEN1KMT2A | |
| SCHEMBL30765668 | 0.71 | GAA (0.50) | LMNAKDM4EALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |