Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765587 | 0.87 | KDM4E (0.42) | KDM4EALDH1A1HSD17B10CYP1A2CYP2C19 | |
| SCHEMBL30765989 | 0.80 | KDM4E (0.51) | KDM4ESMN1; SMN2TSHRALDH1A1HSD17B10 | |
| SCHEMBL30765599 | 0.79 | CTRC (0.54) | KDM4ESMN1; SMN2ALDH1A1HSD17B10ELANE | |
| SCHEMBL30765438 | 0.79 | KDM4E (0.50) | KDM4ESMN1; SMN2TSHRALDH1A1HSD17B10 | |
| SCHEMBL30765993 | 0.70 | KDM4E (0.37) | KDM4EALDH1A1HSD17B10CYP1A2CYP2C19 | |
| SCHEMBL23461153 | 0.69 | KDM4E (0.52) | KDM4ESMN1; SMN2TSHRALDH1A1HSD17B10 | |
| SCHEMBL30765492 | 0.69 | ELANE (0.49) | KDM4ESMN1; SMN2ELANE | |
| SCHEMBL30765683 | 0.69 | TUBB4A (0.47) | KDM4ESMN1; SMN2ELANE | |
| SCHEMBL7965688 | 0.68 | KDM4E (0.45) | KDM4ESMN1; SMN2TSHRALDH1A1HSD17B10 | |
| SCHEMBL4481659 | 0.68 | KDM4E (0.71) | KDM4ESMN1; SMN2TSHRALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |