Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.54 |
| ▸ | LTA4H | P09960 | 4/20 | 0.48 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.48 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.48 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.48 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.47 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7185148 | 0.89 | FFAR1 (0.58) | FFAR1LTA4HPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL8618603 | 0.85 | FDFT1 (0.51) | FFAR1FDFT1DAO | |
| SCHEMBL19322272 | 0.82 | FFAR1 (0.62) | FFAR1LTA4HPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL2201304 | 0.82 | FFAR1 (0.62) | FFAR1LTA4HPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL66826 | 0.82 | SIGMAR1 (0.54) | — | |
| SCHEMBL7300705 | 0.81 | LTA4H (0.64) | FFAR1LTA4HFFAR4EPHX2 | |
| SCHEMBL11057347 | 0.81 | SIGMAR1 (0.52) | — | |
| SCHEMBL19322269 | 0.81 | FFAR1 (0.60) | FFAR1LTA4HPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL11050330 | 0.81 | SIGMAR1 (0.52) | — | |
| SCHEMBL19322285 | 0.81 | FFAR1 (0.60) | FFAR1LTA4HPLAAT3PLAAT5PLAAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| CN-119768164-A | Pharmaceutical compounds for treating complement-mediated disorders | 阿雷克森制药公司 | 2025-04-04 | — | — | CN | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |