Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.64 |
| ▸ | BCHE | P06276 | 4/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.58 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.58 |
| ▸ | MGLL | Q99685 | 2/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7867586 | 0.95 | BCHE (0.62) | LTA4HEPHX2BCHEFFAR1FFAR4 | |
| SCHEMBL2772725 | 0.90 | FFAR1 (0.61) | LTA4HEPHX2BCHEFFAR1FFAR4 | |
| SCHEMBL11464931 | 0.89 | FFAR1 (0.59) | LTA4HEPHX2BCHEFFAR1FFAR4 | |
| SCHEMBL9614962 | 0.84 | LTA4H (0.45) | LTA4HEPHX2BCHEFFAR1FFAR4 | |
| SCHEMBL1171784 | 0.84 | MGLL (0.57) | BCHEMGLLLMNACYP1A2PTGS1 | |
| SCHEMBL12040562 | 0.83 | LTA4H (0.77) | LTA4HEPHX2BCHEFFAR1FFAR4 | |
| SCHEMBL12630258 | 0.83 | LTA4H (0.77) | LTA4HEPHX2BCHEFFAR1FFAR4 | |
| SCHEMBL66826 | 0.82 | SIGMAR1 (0.54) | SLC6A3HDAC6MAOB | |
| SCHEMBL949911 | 0.82 | FFAR1 (0.62) | LTA4HEPHX2FFAR1MAOB | |
| SCHEMBL30765734 | 0.81 | FFAR1 (0.54) | LTA4HEPHX2FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874601-A | Process of protecting a 1,2-aminoalcohol for reductive amination coupling | ABBOTT LABORATORIES (US) | 1999-02-23 | — | — | US | claimed |
| EP-0888282-A1 | PROCESS OF PROTECTING A 1,2-AMINOALCOHOL FOR REDUCTIVE AMINATION COUPLING | Abbott Laboratories (US) | 1999-01-07 | — | — | EP | claimed |
| EP-0658538-B1 | Diagnosis, evaluation and treatment of coronary artery disease by exercise simulation using closed loop drug delivery of an exercise simulating agent beta agonist | GENSIA INC (US) | 1997-10-29 | — | — | EP | claimed |
| WO-1997033857-A1 | PROCESS OF PROTECTING A 1,2-AMINOALCOHOL FOR REDUCTIVE AMINATION COUPLING | ABBOTT LABORATORIES (US) | 1997-09-18 | — | — | WO | claimed |
| EP-0873293-B1 | IMPROVED PROCESS FOR THE PREPARATION OF ALKYL OR ARYL ALDEHYDE INTERMEDIATES | ABBOTT LAB (US) | 2001-07-25 | — | — | EP | disclosed |
| US-5874601-A | Process of protecting a 1,2-aminoalcohol for reductive amination coupling | ABBOTT LABORATORIES (US) | 1999-02-23 | — | — | US | disclosed |
| EP-0888282-A1 | PROCESS OF PROTECTING A 1,2-AMINOALCOHOL FOR REDUCTIVE AMINATION COUPLING | Abbott Laboratories (US) | 1999-01-07 | — | — | EP | disclosed |
| EP-0873293-A1 | IMPROVED PROCESS FOR THE PREPARATION OF ALKYL OR ARYL ALDEHYDE INTERMEDIATES | Abbott Laboratories (US) | 1998-10-28 | — | — | EP | disclosed |
| EP-0658538-B1 | Diagnosis, evaluation and treatment of coronary artery disease by exercise simulation using closed loop drug delivery of an exercise simulating agent beta agonist | GENSIA INC (US) | 1997-10-29 | — | — | EP | disclosed |
| WO-1997033857-A1 | PROCESS OF PROTECTING A 1,2-AMINOALCOHOL FOR REDUCTIVE AMINATION COUPLING | ABBOTT LABORATORIES (US) | 1997-09-18 | — | — | WO | disclosed |
| WO-1997023439-A1 | IMPROVED PROCESS FOR THE PREPARATION OF ALKYL OR ARYL ALDEHYDE INTERMEDIATES | ABBOTT LABORATORIES (US) | 1997-07-03 | — | — | WO | disclosed |
| EP-0329464-B1 | System for the closed-loop administration of an exercise simulating agent | GENSIA INC (US) | 1995-11-02 | — | — | EP | disclosed |
| US-5234404-A | Diagnosis, evaluation and treatment of coronary artery disease by exercise simulation using closed loop drug delivery of an exercise simulating agent beta agonist | GENSIA PHARMACEUTICALS, INC. (US) | 1993-08-10 | — | — | US | disclosed |
| EP-0512065-A4 | APPARATUS AND METHOD FOR IONTOPHORETIC TRANSFER | — | 1992-12-30 | — | — | EP | disclosed |
| EP-0512065-A1 | APPARATUS AND METHOD FOR IONTOPHORETIC TRANSFER | GENSIA PHARMACEUTICALS, INC. (US) | 1992-11-11 | — | — | EP | disclosed |
| US-5108363-A | DIAGNOSIS, EVALUATION AND TREATMENT OF CORONARY ARTERY DISEASE BY EXERCISE SIMULATION USING CLOSED LOOP DRUG DELIVERY OF AN EXERCISE SIMULATING AGENT BETA AGONIST | GENSIA PHARMACEUTICALS, INC. (US) | 1992-04-28 | — | — | US | disclosed |
| WO-1991011215-A1 | APPARATUS AND METHOD FOR IONTOPHORETIC TRANSFER | GENSIA PHARMACEUTICALS, INC. (US) | 1991-08-08 | — | — | WO | disclosed |
| EP-0329464-A2 | System for the closed-loop administration of an exercise simulating agent | GENSIA, INC. (US) | 1989-08-23 | — | — | EP | disclosed |
| US-4262013-A | ANTILIPEMIC AGENTS | SANKYO COMPANY LIMITED (JP) | 1981-04-14 | — | — | US | disclosed |
| US-4198425-A | ANTILIPEMIC AGENTS | SANKYO COMPANY LIMITED (JP) | 1980-04-15 | — | — | US | disclosed |