Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ACACB | O00763 | 9/20 | 0.42 |
| ▸ | ACACA | Q13085 | 8/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | IDH1 | O75874 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31558574 | 0.73 | ELANE (0.46) | ACACBACACAIDH1KDM4E | |
| SCHEMBL23474380 | 0.67 | KDM4E (0.41) | KDM4E | |
| SCHEMBL6649823 | 0.63 | MEN1 (0.44) | MEN1KMT2AL3MBTL1GAATSHR | |
| SCHEMBL23460591 | 0.62 | KDM4E (0.43) | KDM4E | |
| SCHEMBL27959245 | 0.61 | ACACA (0.58) | KMT2AACACBACACAGAA | |
| SCHEMBL16714725 | 0.61 | ACACA (0.58) | KMT2AACACBACACAGAA | |
| Diphenylether SCHEMBL3558137 | 0.61 | LTA4H (0.62) | L3MBTL1LTA4HTSHRLMNAMAPK1 | |
| SCHEMBL13545912 | 0.60 | LTA4H (1.00) | LTA4HLMNAMAPK1 | |
| SCHEMBL3996623 | 0.60 | FAAH (0.55) | MEN1KMT2AACACBACACAL3MBTL1 | |
| SCHEMBL11655422 | 0.60 | LTA4H (0.61) | LTA4HTSHRFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |