Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765962 | 0.91 | KMT2A (0.35) | KMT2ARXFP1NPSR1LMNAKDM4E | |
| SCHEMBL30765676 | 0.88 | SOS1 (0.41) | KMT2ARXFP1LMNAKDM4ETSHR | |
| SCHEMBL30765920 | 0.86 | L3MBTL1 (0.41) | KMT2ARXFP1NPSR1LMNAKDM4E | |
| SCHEMBL30765521 | 0.86 | KMT2A (0.38) | KMT2ARXFP1NPSR1LMNAKDM4E | |
| SCHEMBL30765797 | 0.81 | KMT2A (0.40) | KMT2ARXFP1NPSR1LMNAKDM4E | |
| SCHEMBL30765729 | 0.79 | ALDH1A1 (0.38) | KMT2ARXFP1NPSR1LMNAKDM4E | |
| SCHEMBL30765893 | 0.79 | ALDH1A1 (0.33) | KMT2ARXFP1NPSR1LMNAKDM4E | |
| SCHEMBL30765712 | 0.78 | LMNA (0.35) | NPSR1LMNAKDM4ETSHRHTT | |
| SCHEMBL30765468 | 0.78 | LMNA (0.40) | KMT2ARXFP1NPSR1LMNAKDM4E | |
| SCHEMBL30765991 | 0.77 | ELANE (0.42) | LMNAKDM4EALDH1A1ELANECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |