Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 5/20 | 0.47 |
| ▸ | ELANE | P08246 | 12/20 | 0.42 |
| ▸ | ITK | Q08881 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765787 | 0.92 | CASP1 (0.44) | CASP1ELANEITK | |
| SCHEMBL30765632 | 0.80 | CASP1 (0.42) | CASP1ELANE | |
| SCHEMBL6240894 | 0.79 | ELANE (0.51) | CASP1ELANEMAPT | |
| SCHEMBL5728202 | 0.78 | ELANE (0.54) | CASP1ELANE | |
| SCHEMBL6240974 | 0.74 | RAB9A (0.55) | CASP1ELANEMAPT | |
| SCHEMBL6799310 | 0.74 | RAB9A (0.54) | CASP1ELANE | |
| SCHEMBL30765807 | 0.74 | CASP1 (0.47) | CASP1ELANE | |
| SCHEMBL31558574 | 0.73 | ELANE (0.46) | CASP1ELANE | |
| SCHEMBL6805801 | 0.73 | RAB9A (0.53) | CASP1ELANEMAPT | |
| SCHEMBL30766127 | 0.73 | TUBB4A (0.51) | CASP1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| CN-119768164-A | Pharmaceutical compounds for treating complement-mediated disorders | 阿雷克森制药公司 | 2025-04-04 | — | — | CN | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |