Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRC | Q99895 | 12/20 | 0.47 |
| ▸ | CMA1 | P23946 | 11/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.47 |
| ▸ | ELANE | P08246 | 5/20 | 0.42 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765640 | 0.87 | NTRK1 (0.45) | CTRCCMA1NTRK1NTRK3 | |
| SCHEMBL30765824 | 0.86 | NR1H2 (0.44) | CTRCCMA1NTRK1ELANENTRK3 | |
| SCHEMBL30765506 | 0.80 | NTRK1 (0.51) | CTRCCMA1NTRK1NTRK3 | |
| SCHEMBL30765484 | 0.75 | CMA1 (0.53) | CTRCCMA1NTRK1NTRK3 | |
| SCHEMBL27149698 | 0.75 | NAMPT (0.42) | — | |
| Hydrochloric Acid SCHEMBL30765589 | 0.75 | CMA1 (0.53) | CTRCCMA1NTRK1NTRK3 | |
| SCHEMBL30765887 | 0.74 | NTRK1 (0.41) | NTRK1ELANENTRK3 | |
| SCHEMBL30765718 | 0.73 | NTRK1 (0.45) | CTRCCMA1NTRK1NTRK3 | |
| SCHEMBL6087779 | 0.73 | CTRC (0.52) | CTRCCMA1ELANE | |
| SCHEMBL4795293 | 0.72 | NR1H2 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| CN-119768164-A | Pharmaceutical compounds for treating complement-mediated disorders | 阿雷克森制药公司 | 2025-04-04 | — | — | CN | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |