Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 11/20 | 0.40 |
| ▸ | F2 | P00734 | 3/20 | 0.38 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765824 | 0.89 | NR1H2 (0.44) | NTRK1ELANEF2NTRK3MEN1 | |
| SCHEMBL30765640 | 0.86 | NTRK1 (0.45) | NTRK1NTRK3GAAL3MBTL1 | |
| SCHEMBL30765697 | 0.77 | F2 (0.43) | NTRK1ELANEF2NTRK3CASP1 | |
| SCHEMBL30765810 | 0.74 | CTRC (0.47) | NTRK1ELANENTRK3 | |
| SCHEMBL30765911 | 0.73 | ELANE (0.40) | NTRK1ELANENTRK3CASP1GAA | |
| SCHEMBL30765502 | 0.72 | CASP1 (0.40) | NTRK1ELANEF2NTRK3CASP1 | |
| SCHEMBL30765437 | 0.69 | HDAC6 (0.41) | ELANEF2HTTRAB9AKMT2A | |
| SCHEMBL23461164 | 0.67 | F2 (0.59) | NTRK1F2PRSS1 | |
| SCHEMBL30765955 | 0.67 | TDP1 (0.40) | NTRK1ELANENTRK3MEN1KMT2A | |
| SCHEMBL30765639 | 0.67 | L3MBTL1 (0.41) | NTRK1MEN1HTTRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |