Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 10/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | TACR2 | P21452 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TST | Q16762 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27878821 | 0.81 | IDO1 (0.46) | SLC6A4ADRA2ASLC6A2SLC6A3LMNA | |
| SCHEMBL30765859 | 0.77 | CA2 (0.45) | LMNAHSD17B10PTGS1PTGS2CA1 | |
| SCHEMBL8641530 | 0.77 | CA2 (0.50) | SLC6A4ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL31558448 | 0.76 | DUT (0.39) | SLC6A4GAASLC6A2SLC6A3MAOA | |
| SCHEMBL28015145 | 0.75 | ESR1 (0.55) | SLC6A4ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL1245957 | 0.74 | ALDH1A1 (0.40) | GAAALDH1A1 | |
| SCHEMBL21556357 | 0.73 | ESR1 (0.59) | SLC6A4ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL19019146 | 0.73 | ESR1 (0.59) | SLC6A4ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL12040851 | 0.73 | ESR1 (0.59) | SLC6A4ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL16995434 | 0.73 | SLC6A4 (0.41) | SLC6A4GAASLC6A2SLC6A3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |