Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.71 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.64 |
| ▸ | MAOA | P21397 | 2/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 4/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.59 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.59 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.59 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.59 |
| ▸ | PDE5A | O76074 | 1/20 | 0.59 |
| ▸ | BACE1 | P56817 | 5/20 | 0.59 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.59 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.59 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.58 |
| ▸ | PRKCA | P17252 | 1/20 | 0.58 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 2/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29454740 | 0.91 | IDO1 (0.75) | IDO1CYP19A1MAOAMAOBESR1 | |
| Leachianone G SCHEMBL31237622 | 0.87 | IDO1 (0.81) | IDO1CYP19A1MAOAMAOBESR1 | |
| Leachianone G SCHEMBL6544629 | 0.87 | IDO1 (0.81) | IDO1CYP19A1MAOAMAOBESR1 | |
| Leachianone G SCHEMBL6544631 | 0.87 | IDO1 (0.81) | IDO1CYP19A1MAOAMAOBESR1 | |
| SCHEMBL564110 | 0.83 | IDO1 (1.00) | IDO1CYP19A1MAOAMAOBESR1 | |
| SCHEMBL17626616 | 0.83 | IDO1 (1.00) | IDO1CYP19A1MAOAMAOBESR1 | |
| Munduleaflavanone B SCHEMBL14049994 | 0.81 | ESR1 (0.87) | IDO1CYP19A1MAOAESR1ABCG2 | |
| SCHEMBL29808777 | 0.79 | ABCG2 (0.79) | IDO1CYP19A1MAOAMAOBESR1 | |
| SCHEMBL17626647 | 0.79 | ABCG2 (0.79) | IDO1CYP19A1MAOAMAOBESR1 | |
| SCHEMBL27013448 | 0.79 | ABCG2 (0.79) | IDO1CYP19A1MAOAMAOBESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240016777-A1 | COMPOUNDS AND METHODS FOR TREATING VIRAL INFECTIONS | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 2024-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240016777-A1 | COMPOUNDS AND METHODS FOR TREATING VIRAL INFECTIONS | THPO, SERPINB1, SERPINC1 | IDO1 3111/4885CYP19A1 1668/4885MAOA 1996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.