Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.81 |
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.77 |
| ▸ | ESR1 | P03372 | 3/20 | 0.77 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.77 |
| ▸ | MAOA | P21397 | 2/20 | 0.77 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.77 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.77 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.77 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.77 |
| ▸ | PDE5A | O76074 | 1/20 | 0.77 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.76 |
| ▸ | MAOB | P27338 | 1/20 | 0.75 |
| ▸ | BACE1 | P56817 | 2/20 | 0.71 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.71 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.71 |
| ▸ | ACHE | P22303 | 2/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Leachianone G SCHEMBL6544631 | 1.00 | IDO1 (0.81) | IDO1ABCG2ESR1ESR2MAOA | |
| Leachianone G SCHEMBL31237622 | 1.00 | IDO1 (0.81) | IDO1ABCG2ESR1ESR2MAOA | |
| SCHEMBL17626644 | 0.91 | ABCG2 (0.79) | IDO1ABCG2ESR1ESR2MAOA | |
| SCHEMBL27013448 | 0.91 | ABCG2 (0.79) | IDO1ABCG2ESR1ESR2MAOA | |
| SCHEMBL29808777 | 0.91 | ABCG2 (0.79) | IDO1ABCG2ESR1ESR2MAOA | |
| SCHEMBL17626647 | 0.91 | ABCG2 (0.79) | IDO1ABCG2ESR1ESR2MAOA | |
| SCHEMBL29454740 | 0.90 | IDO1 (0.75) | IDO1ABCG2ESR1ESR2MAOA | |
| SCHEMBL564110 | 0.89 | IDO1 (1.00) | IDO1ABCG2ESR1ESR2MAOA | |
| SCHEMBL17626616 | 0.89 | IDO1 (1.00) | IDO1ABCG2ESR1ESR2MAOA | |
| Sophoraflavanone L SCHEMBL30766211 | 0.87 | IDO1 (0.71) | IDO1ABCG2ESR1ESR2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118370763-A | Application of isopentenyl flavonoid compound in kuh-seng extract in preparation of product for preventing and treating pathogenic bacteria of dairy cows | 山东方舟生物科技有限公司 | 2024-07-23 | — | — | CN | claimed |
| CN-118304334-A | Preparation and application of traditional Chinese medicine fructus rhodomyrti liver protection active ingredient | 北京工业大学 | 2024-07-09 | — | — | CN | claimed |
| US-11517556-B2 | Composition for BKCa channel activation | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2022-12-06 | — | — | US | claimed |
| US-20200069640-A1 | COMPOSITION FOR BKCA CHANNEL ACTIVATION | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2020-03-05 | — | — | US | claimed |
| US-20190083456-A1 | COMPOSITION FOR BKCA CHANNEL ACTIVATION | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2019-03-21 | — | — | US | claimed |
| EP-1294388-B1 | EXTRACTS FROM SOPHORA SPECIES, METHOD FOR PRODUCING THE SAME AND THEIR USE | SCHWABE WILLMAR GMBH & CO (DE) | 2004-01-07 | — | — | EP | claimed |
| CN-118370763-B | Application of isopentenyl flavonoid compound in kuh-seng extract in preparation of product for preventing and treating pathogenic bacteria of dairy cows | 山东方舟生物科技有限公司 | 2024-10-08 | — | — | CN | disclosed |
| CN-118370763-A | Application of isopentenyl flavonoid compound in kuh-seng extract in preparation of product for preventing and treating pathogenic bacteria of dairy cows | 山东方舟生物科技有限公司 | 2024-07-23 | — | — | CN | disclosed |
| CN-114146083-B | Sophora japonica extract and active ingredient and application thereof in preparation of products for treating glycolipid metabolism comprehensive disorder | 天津科技大学 | 2024-05-24 | — | — | CN | disclosed |
| US-11517556-B2 | Composition for BKCa channel activation | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2022-12-06 | — | — | US | disclosed |
| US-11479537-B2 | T-type calcium channel inhibitor | KINKI UNIVERSITY (JP) | 2022-10-25 | — | — | US | disclosed |
| EP-3000465-B1 | T-TYPE CALCIUM CHANNEL INHIBITOR | UNIV KINKI (JP) | 2021-03-31 | — | — | EP | disclosed |
| US-20200308132-A1 | T-TYPE CALCIUM CHANNEL INHIBITOR | NATIONAL UNIVERSITY CORPORATION UNIVERSITY OF TOYAMA (JP) | 2020-10-01 | — | — | US | disclosed |
| US-10633358-B2 | T-type calcium channel inhibitor | KINKI UNIVERSITY (JP) | 2020-04-28 | — | — | US | disclosed |
| US-20200069640-A1 | COMPOSITION FOR BKCA CHANNEL ACTIVATION | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2020-03-05 | — | — | US | disclosed |
| US-20190083456-A1 | COMPOSITION FOR BKCA CHANNEL ACTIVATION | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2019-03-21 | — | — | US | disclosed |
| US-20180132516-A1 | POSITIVE ALLOSTERIC MODULATORS OF SWEET TASTE | SENSORYGEN INC (US) | 2018-05-17 | — | — | US | disclosed |
| US-20180065947-A1 | T-TYPE CALCIUM CHANNEL INHIBITOR | UNIV KINKI (JP) | 2018-03-08 | — | — | US | disclosed |
| US-20160096815-A1 | T-TYPE CALCIUM CHANNEL INHIBITOR | KINKI UNIVERSITY (JP) | 2016-04-07 | — | — | US | disclosed |
| EP-3000465-A1 | T-TYPE CALCIUM CHANNEL INHIBITOR | Kinki University (JP) | 2016-03-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160096815-A1 | T-TYPE CALCIUM CHANNEL INHIBITOR | CACNA1G, CACNA1H, CACNA1I | IDO1 3029/4885ABCG2 1660/4885ESR1 3507/4885 |
| US-20200069640-A1 | COMPOSITION FOR BKCA CHANNEL ACTIVATION | KCNAB1, KCNN3, KCNC1 | IDO1 3614/4885ABCG2 2102/4885ESR1 3513/4885 |
| US-20180065947-A1 | T-TYPE CALCIUM CHANNEL INHIBITOR | CACNA1G, CACNA1H, CACNA1I | IDO1 3036/4885ABCG2 1755/4885ESR1 3527/4885 |
| US-11517556-B2 | Composition for BKCa channel activation | KCNAB1, KCNN3, KCNC1 | IDO1 3614/4885ABCG2 2102/4885ESR1 3513/4885 |
| US-11479537-B2 | T-type calcium channel inhibitor | CACNA1H, CACNA1I, CACNA1G | IDO1 1814/4885ABCG2 1721/4885ESR1 3841/4885 |
| US-20190083456-A1 | COMPOSITION FOR BKCA CHANNEL ACTIVATION | KCNAB1, KCNN3, KCNC1 | IDO1 3614/4885ABCG2 2102/4885ESR1 3513/4885 |
| US-20200308132-A1 | T-TYPE CALCIUM CHANNEL INHIBITOR | CACNA1H, CACNA1I, CACNA1G | IDO1 1814/4885ABCG2 1721/4885ESR1 3841/4885 |
| US-10633358-B2 | T-type calcium channel inhibitor | CACNA1G, CACNA1H, CACNA1I | IDO1 3036/4885ABCG2 1755/4885ESR1 3527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.