⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4333845 | 0.97 | — | — | |
| Methacrylic Acid SCHEMBL6672880 | 0.88 | MAPT (0.36) | — | |
| SCHEMBL3763074 | 0.84 | NPC1 (0.36) | — | |
| SCHEMBL380757 | 0.83 | — | — | |
| SCHEMBL4052770 | 0.81 | GPR84 (0.39) | — | |
| SCHEMBL15766380 | 0.79 | GPR84 (0.42) | — | |
| SCHEMBL2553351 | 0.79 | GPR84 (0.42) | — | |
| SCHEMBL29160727 | 0.79 | MAPT (0.38) | — | |
| SCHEMBL16309322 | 0.79 | MAPT (0.47) | — | |
| SCHEMBL21815374 | 0.79 | NOS3 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 373 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3344630-B1 | SUBSTITUTED 1,2-DIHYDRO-3H-PYRROLO[1,2-C]IMIDAZOL-3-ONE ANTIBACTERIAL COMPOUNDS | IDORSIA PHARMACEUTICALS LTD (CH) | 2020-12-09 | — | — | EP | claimed |
| EP-3609888-A1 | FARNESOID X RECEPTOR AGONISTS AND USES THEREOF | Metacrine, Inc. (US) | 2020-02-19 | — | — | EP | claimed |
| US-10314823-B2 | Substituted 1,2-dihydro-3H-pyrrolo[1,2-c]imidazol-3-one antibacterial compounds | IDORSIA PHARMACEUTICALS LTD (CH) | 2019-06-11 | — | — | US | claimed |
| WO-2018170182-A1 | FARNESOID X RECEPTOR AGONISTS AND USES THEREOF | METACRINE, INC. (US) | 2018-09-20 | — | — | WO | claimed |
| US-20180250273-A1 | SUBSTITUTED 1,2-DIHYDRO-3H-PYRROLO[1,2-c]IMIDAZOL-3-ONE ANTIBACTERIAL COMPOUNDS | IDORSIA PHARMACEUTICALS LTD. (CH) | 2018-09-06 | — | — | US | claimed |
| US-8614211-B2 | Certain chemical entities, compositions, and methods | NEUPHARMA, INC. (US) | 2013-12-24 | — | — | US | claimed |
| US-20130040945-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | NEUPHARMA, INC. | 2013-02-14 | — | — | US | claimed |
| WO-2013023145-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | NEUPHARMA, INC. (US) | 2013-02-14 | — | — | WO | claimed |
| WO-2009147216-A1 | NEW PYRIDINE DERIVATIVES AS LEPTIN RECEPTOR MODULATOR MIMETICS | BIOVITRUM AB (PUBL) (SE) | 2009-12-10 | — | — | WO | claimed |
| US-20250051350-A1 | Dihydroartemisinin derivatives and the treatment of fibrotic diseases | GreenStone Biosciences, Inc. (US) | 2025-02-13 | — | — | US | disclosed |
| CN-115461055-B | Prodrugs of neuroactive steroids | 腾盛博药生物科技有限公司 | 2025-01-28 | — | — | CN | disclosed |
| US-20240228503-A1 | TRIAZOLE-SUBSTITUTED IMIDAZO[1,2-A]PYRIMIDINES AS CGAS INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2024-07-11 | — | — | US | disclosed |
| EP-3883926-B1 | BIS-OCTAHYDROPHENANTHRENE CARBOXAMIDE DERIVATIVES AND PROTEIN CONJUGATES THEREOF FOR USE AS LXR AGONISTS | REGENERON PHARMA (US) | 2024-07-10 | — | — | EP | disclosed |
| WO-2024144371-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING PENDRIN | ARBORMED CO., LTD. (KR) | 2024-07-04 | — | — | WO | disclosed |
| WO-2000006606-A2 | ERYTHROMYCIN DERIVATIVES WITH ANTIBIOTIC ACTIVITY | ZAMBON GROUP S.P.A. (IT) | 2000-02-10 | — | — | WO | disclosed |
| CN-1234023-A | 4-aminoethoxy indoes as dopamin D2 agonists and as 5HT1A ligands | AMERICAN HOME PROD (US) | 1999-11-03 | — | — | CN | disclosed |
| CN-1234024-A | 4-aminoethoxy indolone derivatives | AMERICAN HOME PROD (US) | 1999-11-03 | — | — | CN | disclosed |
| WO-1999015129-A2 | SELECTIVE cPLA2 INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-04-01 | — | — | WO | disclosed |
| US-4607051-A | Carbamic acid compound and use as a pesticide | HOFFMANN-LA ROCHE INC. (US) | 1986-08-19 | — | — | US | disclosed |
| US-4413010-A | Carbamic acid esters and use as pesticides | HOFFMANN-LA ROCHE INC. (US) | 1983-11-01 | — | — | US | disclosed |