Methacrylic Acid

Methacrylic Acid

SCHEMBL6672880

C=C(C)C(=O)O.CN(CCO)C(=O)O

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.36
CHRNB2 P17787 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA4 P43681 1/20 0.34
TGFBR1 P36897 1/20 0.31
CNR1 P21554 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL307669 0.88
Hydrochloric Acid SCHEMBL4333845 0.85
Methacrylic Acid SCHEMBL347055 0.84 MAPT (0.38) MAPTTGFBR1TDP1
Methacrylic Acid SCHEMBL43929 0.84 MAPT (0.38) MAPTTGFBR1TDP1
Methacrylic Acid SCHEMBL3423292 0.84 MAPT (0.57) MAPTCHRNB2CHRNA4TGFBR1TDP1
Trolamine SCHEMBL345855 0.81 MAPT (0.37) MAPTTGFBR1TDP1
Trolamine SCHEMBL44442 0.81 MAPT (0.37) MAPTTGFBR1TDP1
Trolamine SCHEMBL43636 0.81 MAPT (0.37) MAPTTGFBR1TDP1
SCHEMBL158624 0.79 MAPT (0.38) MAPTCHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL29160727 0.79 MAPT (0.38) MAPTCHRNB2CHRNB4CHRNA3CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0675141-B2 Copolymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof UNION CARBIDE CHEM PLASTIC (US) 2004-09-29 EP claimed
EP-0675141-B1 Copolymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof UNION CARBIDE CHEM PLASTIC (US) 1998-06-03 EP claimed