Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | PTGES | O14684 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31375546 | 0.85 | RAB9A (0.40) | MAPTRAB9AL3MBTL1CASP3SENP8 | |
| SCHEMBL31664992 | 0.85 | KDM1A (0.46) | MAPTRAB9AL3MBTL1CASP3SENP8 | |
| SCHEMBL21816559 | 0.82 | RAB9A (0.50) | MAPTRAB9AL3MBTL1CASP3SENP8 | |
| SCHEMBL30767487 | 0.80 | CYP11B1 (0.37) | MAPTRAB9AL3MBTL1CASP3SENP8 | |
| SCHEMBL31375571 | 0.80 | CHRNA7 (0.46) | MAPTRAB9AL3MBTL1CASP3SENP8 | |
| SCHEMBL21816578 | 0.79 | RAB9A (0.43) | MAPTRAB9AL3MBTL1CASP3SENP8 | |
| SCHEMBL21816554 | 0.79 | MAPT (0.43) | MAPTRAB9AL3MBTL1CASP3SENP8 | |
| SCHEMBL21816553 | 0.79 | RAB9A (0.43) | MAPTRAB9AL3MBTL1CASP3SENP8 | |
| SCHEMBL9061973 | 0.79 | RAB9A (0.52) | MAPTRAB9AL3MBTL1CASP3SENP8 | |
| Hydrochloric Acid SCHEMBL30767633 | 0.79 | CHRM5 (0.43) | MAPTRAB9AL3MBTL1CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568960-A1 | BICYCLIC TETRAHYDROAZEPINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024033458-A1 | BICYCLIC TETRAHYDROAZEPINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2024-02-15 | — | — | WO | disclosed |