Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 9/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 9/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8239627 | 0.83 | RAB9A (0.49) | CYP11B1CYP11B2RAB9AL3MBTL1MAPT | |
| SCHEMBL30767655 | 0.83 | KDM1A (0.49) | CYP11B1CYP11B2RAB9AMAPTNPC1 | |
| SCHEMBL31375485 | 0.83 | RAB9A (0.39) | CYP11B1CYP11B2RAB9AL3MBTL1MAPT | |
| SCHEMBL30767657 | 0.80 | MAPT (0.40) | CYP11B1CYP11B2RAB9AL3MBTL1MAPT | |
| SCHEMBL17610081 | 0.77 | CYP11B1 (0.47) | CYP11B1CYP11B2RAB9AL3MBTL1NPC1 | |
| SCHEMBL31375514 | 0.77 | KDM1A (0.45) | CYP11B1CYP11B2L3MBTL1AURKAABL1 | |
| SCHEMBL17092743 | 0.75 | CA1 (0.38) | L3MBTL1MAPK1ATM | |
| SCHEMBL21035108 | 0.75 | CNR2 (0.44) | CYP11B1CYP11B2RAB9AL3MBTL1MAPT | |
| SCHEMBL30767444 | 0.74 | KIF11 (0.40) | CYP11B1CYP11B2RAB9AL3MBTL1MAPT | |
| SCHEMBL21035639 | 0.74 | CYP11B1 (0.54) | CYP11B1CYP11B2RAB9AL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568960-A1 | BICYCLIC TETRAHYDROAZEPINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024033458-A1 | BICYCLIC TETRAHYDROAZEPINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2024-02-15 | — | — | WO | disclosed |