Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.37 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.33 |
| ▸ | CFD | P00746 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | GPER1 | Q99527 | 2/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4433133 | 0.81 | MET (0.48) | RXRARXRBRXRGAGBL2PTGDR2 | |
| SCHEMBL30767752 | 0.79 | RXRA (0.45) | RXRARXRBRXRGAGBL2PTGDR2 | |
| SCHEMBL30767760 | 0.77 | PTGDR2 (0.45) | RXRARXRBRXRGPTGDR2FFAR4 | |
| SCHEMBL17653810 | 0.77 | PTGS2 (0.46) | PTGS2ACHEFFAR4 | |
| SCHEMBL30767770 | 0.70 | RXRA (0.43) | RXRARXRBRXRGAGBL2PTGDR2 | |
| SCHEMBL8512 | 0.69 | AKR1B1 (0.48) | RXRARXRBRXRGAGBL2 | |
| SCHEMBL1560060 | 0.68 | MET (0.48) | CFDMETKCNH2 | |
| Hydrochloric Acid SCHEMBL3297493 | 0.67 | AKR1B1 (0.46) | RXRARXRBRXRGAGBL2 | |
| SCHEMBL23535770 | 0.67 | BCL2L1 (0.46) | RXRARXRBRXRGACHE | |
| SCHEMBL30767774 | 0.67 | RXRA (0.56) | RXRARXRBRXRGFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024014851-A1 | NOVEL PURINE DERIVATIVE COMPOUNDS AS HIF-1 PROTEIN INHIBITOR | 주식회사 넥스트젠바이오사이언스 | 2024-01-18 | — | — | WO | disclosed |