Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | RAF1 | P04049 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24749691 | 1.00 | RXFP1 (0.41) | RXFP1TRPV1KMT2ANPC1RAB9A | |
| SCHEMBL24749762 | 0.86 | RXFP1 (0.40) | RXFP1KMT2AKDRRAF1BRAF | |
| SCHEMBL24749750 | 0.86 | LMNA (0.45) | — | |
| SCHEMBL31009416 | 0.86 | LMNA (0.45) | — | |
| SCHEMBL24750237 | 0.85 | BRAF (0.42) | RXFP1KMT2AKDRBRAFMEN1 | |
| SCHEMBL24750232 | 0.79 | RXRA (0.37) | TRPV1KMT2AMMP2MMP9MMP1 | |
| SCHEMBL29344673 | 0.78 | MEN1 (0.38) | RXFP1KMT2ANPC1RAB9ABRAF | |
| SCHEMBL29937909 | 0.77 | P2RX7 (0.40) | TRPV1KMT2AMMP2MMP9MMP1 | |
| SCHEMBL24750190 | 0.77 | P2RX7 (0.40) | TRPV1KMT2AMMP2MMP9MMP1 | |
| SCHEMBL29149304 | 0.77 | CNR2 (0.41) | KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117500786-A | TEAD inhibitors | 奥赖恩公司 | 2024-02-02 | — | — | CN | disclosed |