Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.43 |
| ▸ | CLK1 | P49759 | 2/20 | 0.43 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26696369 | 1.00 | GUSB (0.46) | GUSBJAK2DYRK1ACLK1DYRK2 | |
| SCHEMBL26876461 | 0.88 | JAK2 (0.45) | GUSBJAK2DYRK1ACLK1DYRK2 | |
| SCHEMBL26696374 | 0.83 | GUSB (0.55) | GUSBJAK2DYRK1ACLK1DYRK2 | |
| SCHEMBL30768447 | 0.83 | GUSB (0.55) | GUSBJAK2DYRK1ACLK1DYRK2 | |
| SCHEMBL30768400 | 0.80 | MTNR1A (0.44) | GUSBDYRK1ACLK1DYRK2DYRK1B | |
| SCHEMBL26696363 | 0.80 | MTNR1A (0.44) | GUSBDYRK1ACLK1DYRK2DYRK1B | |
| SCHEMBL26696394 | 0.78 | GUSB (0.52) | GUSBDYRK1A | |
| SCHEMBL26696343 | 0.76 | JAK2 (0.44) | GUSBJAK2DYRK1A | |
| SCHEMBL30768359 | 0.75 | CDC7 (0.47) | GUSB | |
| SCHEMBL26873386 | 0.75 | CDC7 (0.47) | GUSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382926-A1 | COMPOUNDS AND USES THEREOF | THE UNIVERSITY OF THE WEST INDIES (TT) | 2023-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230382926-A1 | COMPOUNDS AND USES THEREOF | CFTR, CCL11, CEL | GUSB 111/4885JAK2 72/4885DYRK1A 4777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.