Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30769074 | 0.86 | MAOB (0.47) | MAOBBACE1L3MBTL1MEN1PKM | |
| SCHEMBL30769131 | 0.85 | MAOB (0.44) | MAOBPTPN1CACNA1BBACE1NPC1 | |
| SCHEMBL30769423 | 0.78 | RAB9A (0.47) | MAOBLTB4RLTB4R2BACE1ALOX5 | |
| SCHEMBL2434378 | 0.71 | MAOB (0.51) | MAOBLTB4RLTB4R2ALOX5NPC1 | |
| SCHEMBL29925382 | 0.71 | MAOB (0.54) | MAOBALOX5L3MBTL1 | |
| SCHEMBL2133357 | 0.71 | MAOB (0.54) | MAOBALOX5L3MBTL1 | |
| SCHEMBL30768565 | 0.70 | MAOB (0.43) | MAOBPTPN1LTB4RLTB4R2BACE1 | |
| SCHEMBL30768454 | 0.70 | FFAR1 (0.47) | MAOBPTPN1BACE1ALOX5RAB9A | |
| SCHEMBL30768939 | 0.69 | PKM (0.55) | MAOBLTB4RLTB4R2CACNA1BPKM | |
| SCHEMBL31748829 | 0.69 | MAOB (0.54) | MAOBBACE1ALOX5MEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543871-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND USE THEREOF | Relay Therapeutics, Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| WO-2024006781-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |