Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30768454 | 0.84 | FFAR1 (0.47) | MAOBMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL30768868 | 0.79 | MAOB (0.41) | MAOBMEN1KMT2ARAB9AKDM4E | |
| SCHEMBL31484604 | 0.79 | ALDH1A1 (0.42) | MEN1KMT2ARAB9AMAPTALDH1A1 | |
| SCHEMBL30769423 | 0.79 | RAB9A (0.47) | MAOBMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL28866139 | 0.79 | MAOB (0.54) | MAOBRAB9AMAPTSMN1; SMN2 | |
| SCHEMBL3110938 | 0.78 | L3MBTL1 (0.49) | MAPTALDH1A1NPC1 | |
| SCHEMBL25273703 | 0.78 | MAOB (0.50) | MAOBMEN1KMT2ARAB9AKDM4E | |
| SCHEMBL14110346 | 0.78 | TRPM8 (0.50) | MEN1KMT2APOLBBACE1LTA4H | |
| SCHEMBL30769074 | 0.76 | MAOB (0.47) | MAOBMEN1KMT2AKDM4EMAPT | |
| SCHEMBL2133357 | 0.76 | MAOB (0.54) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543871-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND USE THEREOF | Relay Therapeutics, Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| WO-2024006781-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |