⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL182562 | 1.00 | — | — | |
| SCHEMBL31444457 | 0.79 | CES2 (0.38) | — | |
| SCHEMBL1162776 | 0.79 | CES2 (0.38) | — | |
| SCHEMBL31444326 | 0.75 | TAAR1 (0.32) | — | |
| SCHEMBL1863530 | 0.75 | TAAR1 (0.32) | — | |
| SCHEMBL1125226 | 0.75 | ACHE (0.37) | — | |
| SCHEMBL5083110 | 0.74 | — | — | |
| SCHEMBL15530228 | 0.74 | ALDH1A1 (0.36) | — | |
| SCHEMBL1256658 | 0.72 | — | — | |
| SCHEMBL4479531 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543871-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND USE THEREOF | Relay Therapeutics, Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| WO-2025072451-A1 | RAS-PI3K INHIBITORS FOR THE TREATMENT OF CANCER AND IMMUNOLOGICAL DISEASES | VIVIDION THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |
| WO-2024006781-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |