Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 3/20 | 0.43 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30769413 | 0.80 | MAOB (0.48) | MPOELANECYP24A1 | |
| SCHEMBL8309725 | 0.80 | ESR1 (0.52) | MPOELANEMIFCYP26A1ESR1 | |
| SCHEMBL30768918 | 0.79 | MPO (0.46) | MPOELANEMIFCYP26A1CYP24A1 | |
| SCHEMBL31285043 | 0.77 | MPO (0.66) | MPOELANEMIFCYP26A1ESR1 | |
| SCHEMBL4802603 | 0.76 | MPO (0.60) | MPOELANEESR1CYP17A1CYP3A4 | |
| SCHEMBL12365375 | 0.74 | KDM4E (0.45) | MPOELANEMAPK14MAPTKMT2A | |
| SCHEMBL6858889 | 0.73 | MPO (0.57) | MPOELANEMIFCYP26A1ESR1 | |
| SCHEMBL12365372 | 0.73 | MAPK14 (0.43) | MPOMAPK14MAPTKMT2ATDP1 | |
| SCHEMBL14267917 | 0.72 | MPO (0.56) | MPOELANECYP17A1CYP3A4CYP11B1 | |
| SCHEMBL30769328 | 0.72 | MPO (0.46) | MPOELANECYP24A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543871-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND USE THEREOF | Relay Therapeutics, Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| WO-2024006781-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |