Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14267917 | 0.92 | MPO (0.56) | MPOCYP3A4ELANECYP11B2CYP17A1 | |
| SCHEMBL6858889 | 0.91 | MPO (0.57) | MPOCYP3A4ELANEALDH1A1LMNA | |
| SCHEMBL8309725 | 0.88 | ESR1 (0.52) | MPOCYP3A4ELANECYP11B2CYP17A1 | |
| SCHEMBL3785482 | 0.87 | MPO (0.55) | MPOCYP3A4ELANECYP11B2CYP17A1 | |
| SCHEMBL7633335 | 0.87 | MPO (0.51) | MPOCYP3A4ELANECYP11B2ABCB1 | |
| SCHEMBL8310384 | 0.86 | BACE1 (0.49) | MPOCYP3A4ELANECYP11B2CYP17A1 | |
| SCHEMBL6789105 | 0.84 | PTPN1 (0.46) | MPOCYP3A4ELANEABCB1ALDH1A1 | |
| SCHEMBL7633012 | 0.84 | MPO (0.54) | MPOELANEABCB1ALDH1A1 | |
| SCHEMBL23297253 | 0.83 | MPO (0.50) | MPOELANEESR1 | |
| SCHEMBL114809 | 0.80 | EBP (0.65) | MPOABCB1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7332260-B2 | Naphthopyrans annelated in C5-C6, their preparation and compositions and (CO)polymer matrices containing them | CORNING INCORPORATED (US) | 2008-02-19 | — | — | US | disclosed |
| EP-1119560-B1 | NAPHTHOPYRANS ANNELATED IN C5-C6, THEIR PREPARATION AND COMPOSITIONS AND (CO) POLYMER MATRICES CONTAINING THEM | CORNING SA (FR) | 2003-03-05 | — | — | EP | disclosed |
| US-6506538-B1 | Ophthalmic lenses, contact lenses, solar protection glasses, filters, camera optics or photographic apparatus optics or other optical devices | CORNING S.A. (FR) | 2003-01-14 | — | — | US | disclosed |
| US-20020197562-A1 | Naphthopyrans annelated in C5-C6, their preparation and compositions and (CO)polymer matrices containing them | BREYNE OLIVIER (FR) | 2002-12-26 | — | — | US | disclosed |
| EP-1119560-A1 | NAPHTHOPYRANS ANNELATED IN C5-C6, THEIR PREPARATION AND COMPOSITIONS AND (CO) POLYMER MATRICES CONTAINING THEM | Corning S.A. (FR) | 2001-08-01 | — | — | EP | disclosed |
| WO-2000015628-A1 | NAPHTHOPYRANS ANNELATED IN C5-C6, THEIR PREPARATION AND COMPOSITIONS AND (CO) POLYMER MATRICES CONTAINING THEM | CORNING S.A. (FR) | 2000-03-23 | — | — | WO | disclosed |
| US-4927838-A | CARDIOVASCULAR DISORDERS | HOFFMAN-LA ROCHE INC. (US) | 1990-05-22 | — | — | US | disclosed |
| EP-0298466-A2 | Substituted alkene carboxylic acid amides and derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1989-01-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020197562-A1 | Naphthopyrans annelated in C5-C6, their preparation and compositions and (CO)polymer matrices containing them | C5, CCNC, C9 | MPO 1818/4885CYP3A4 605/4885ELANE 1998/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.