Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1A | P54750 | 2/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PRKDC | P78527 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31473135 | 0.90 | RIPK1 (0.34) | HDAC6PIK3C3MEN1KMT2AHCRTR1 | |
| SCHEMBL31757976 | 0.82 | GSK3B (0.32) | HDAC6GRM2HCRTR1HCRTR2MAPT | |
| SCHEMBL31473146 | 0.81 | GAA (0.33) | ALDH1A1GAA | |
| SCHEMBL31473149 | 0.73 | KMT2A (0.42) | MEN1KMT2AHCRTR1HCRTR2KDM4E | |
| SCHEMBL31758029 | 0.72 | PLA2G10 (0.37) | HDAC6MEN1KMT2AHCRTR1HCRTR2 | |
| SCHEMBL303241 | 0.71 | EHMT2 (0.38) | PIK3C3MEN1KMT2ATDP1KDM4E | |
| SCHEMBL31473165 | 0.66 | ITGB3 (0.35) | HDAC6PIK3C3ALDH1A1 | |
| SCHEMBL31436236 | 0.62 | CMA1 (0.51) | PDE1APDE1BPDE1CMEN1KMT2A | |
| SCHEMBL31473158 | 0.62 | EHMT2 (0.40) | HDAC6 | |
| SCHEMBL14172061 | 0.62 | GRM2 (0.39) | GRM2MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260008784-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR MEDICAL USE FOR THE TREATMENT OR PREVENTION OF VASCULAR DISEASES | VASTHERA CO LTD (KR) | 2026-01-08 | — | — | US | disclosed |
| EP-4547673-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR MEDICAL USE FOR THE TREATMENT OR PREVENTION OF VASCULAR DISEASES | VASTHERA Co. Ltd. (KR) | 2025-05-07 | — | — | EP | disclosed |
| CN-119403810-A | Compounds, pharmaceutical compositions containing them and their medical use for the treatment or prevention of vascular diseases | 瓦斯塞拉股份有限公司 | 2025-02-07 | — | — | CN | disclosed |
| WO-2024005556-A1 | Compounds, pharmaceutical compositions containing them and their medical use for the treatment or prevention of vascular diseases | VASTHERA CO., LTD. (KR) | 2024-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260008784-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR MEDICAL USE FOR THE TREATMENT OR PREVENTION OF VASCULAR DISEASES | PRDX1, PRDX2, PRDX6 | PDE1A 1620/4885PDE1B 1610/4885PDE1C 1622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.