SCHEMBL30769759

SCHEMBL30769759

CN1CCN(c2nc3c(C4CCNCC4)ccnc3[nH]2)CC1

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ IRAK4 Q9NWZ3 1/20 0.40
▸ PIM1 P11309 3/20 0.39
▸ NPC1 O15118 1/20 0.38
▸ RAB9A P51151 1/20 0.38
▸ KCNH2 Q12809 1/20 0.38
▸ MAP3K12 Q12852 1/20 0.37
▸ HRH4 Q9H3N8 7/20 0.37
▸ CCNT1 O60563 1/20 0.36
▸ CDK9 P50750 1/20 0.36
▸ HTR3A P46098 1/20 0.36
▸ IKBKB O14920 1/20 0.35
▸ HRH3 Q9Y5N1 2/20 0.35
▸ HTR6 P50406 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27059667 1.00 IRAK4 (0.40) IRAK4PIM1NPC1RAB9AKCNH2
Bromide SCHEMBL27035319 0.99 IRAK4 (0.40) IRAK4PIM1NPC1RAB9AKCNH2
SCHEMBL27059609 0.86 LRRK2 (0.42) IRAK4PIM1
Hydrochloric Acid SCHEMBL27035229 0.85 LRRK2 (0.41) IRAK4PIM1
Bromide SCHEMBL27035540 0.85 LRRK2 (0.41) IRAK4PIM1
SCHEMBL27035288 0.84 PARP1 (0.41) MAP3K12CCNT1CDK9HTR6
SCHEMBL30769931 0.84 PARP1 (0.41) MAP3K12CCNT1CDK9HTR6
SCHEMBL27058632 0.80 CDK9 (0.38) MAP3K12CCNT1CDK9HTR6
Hydrochloric Acid SCHEMBL30769764 0.79 CDK9 (0.37) MAP3K12CCNT1CDK9HTR6
SCHEMBL24683422 0.77 PARP1 (0.41) PIM1CCNT1CDK9HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260022116-A1 IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF SANOFI-AVENTIS RECHERCHE & DÉVELOPPEMENT (FR) 2026-01-22 — — US disclosed
EP-4558500-A1 IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF Sanofi (FR) 2025-05-28 — — EP disclosed
WO-2024017977-A1 IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF SANOFI (FR) 2024-01-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022116-A1 IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF MAPK1, MAPK3, MAPK6 IRAK4 642/4885PIM1 660/4885NPC1 1188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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