SCHEMBL30770799

SCHEMBL30770799

c1ccc(CNc2cccs2)nc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.56
MAOB P27338 3/20 0.56
ALDH1A1 P00352 3/20 0.54
KDM4E B2RXH2 2/20 0.54
MAPT P10636 2/20 0.54
GBA1 P04062 1/20 0.54
SMN1; SMN2 Q16637 3/20 0.50
TNF P01375 2/20 0.49
POLB P06746 2/20 0.49
NOD1 Q9Y239 2/20 0.49
PKM P14618 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
PTPN11 Q06124 1/20 0.47
NPC1 O15118 5/20 0.46
RAB9A P51151 4/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
TP53 P04637 1/20 0.46
HPGD P15428 1/20 0.46
HTT P42858 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13574507 0.76 MAOA (0.56) MAOAMAOBALDH1A1KDM4EMAPT
SCHEMBL1244338 0.75 MAOA (0.70) MAOAMAOBALDH1A1KDM4EMAPT
SCHEMBL17997542 0.75 CHRM2 (0.51) MAOAMAOBALDH1A1KDM4EMAPT
SCHEMBL29846220 0.74 MAOA (0.68) MAOAMAOBALDH1A1KDM4EMAPT
SCHEMBL25920692 0.73
SCHEMBL29941075 0.73 MAOA (0.79) MAOAMAOBALDH1A1KDM4EMAPT
SCHEMBL229311 0.72 CXCR4 (0.68) MAOAMAOBALDH1A1KDM4ESMN1; SMN2
SCHEMBL5941249 0.72 MEN1 (0.49) ALDH1A1KDM4EMAPTGBA1SMN1; SMN2
SCHEMBL30487250 0.72 CXCR4 (0.68) MAOAMAOBALDH1A1KDM4ESMN1; SMN2
SCHEMBL522503 0.72 MAOA (1.00) MAOAMAOBALDH1A1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250391519-A1 CHEMICAL SYNTHESIS PLATFORM UNIV GLASGOW COURT (GB) 2025-12-25 US disclosed
EP-4548355-A1 CHEMICAL SYNTHESIS PLATFORM The University Court Of The University Of Glasgow (GB) 2025-05-07 EP disclosed
WO-2024003151-A1 CHEMICAL SYNTHESIS PLATFORM THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW (GB) 2024-01-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250391519-A1 CHEMICAL SYNTHESIS PLATFORM SET, CBS, COASY MAOA 1439/4885MAOB 819/4885ALDH1A1 2847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.