SCHEMBL30487250

SCHEMBL30487250

c1ccc(CNc2ccccn2)nc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCR4 P61073 1/20 0.68
CYP1A2 P05177 1/20 0.67
MAOA P21397 3/20 0.66
MAOB P27338 3/20 0.66
FABP1 P07148 1/20 0.66
FABP6 P51161 1/20 0.66
NPC1 O15118 5/20 0.62
RAB9A P51151 4/20 0.62
KDM4E B2RXH2 3/20 0.62
HPGD P15428 2/20 0.62
SMN1; SMN2 Q16637 2/20 0.62
TP53 P04637 2/20 0.62
HTT P42858 1/20 0.62
HSD17B10 Q99714 1/20 0.62
ALDH1A1 P00352 2/20 0.58
APP P05067 1/20 0.55
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
GAA P10253 1/20 0.53
TSHR P16473 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL229311 1.00 CXCR4 (0.68) CXCR4CYP1A2MAOAMAOBFABP1
SCHEMBL3955545 0.83 ALDH1A1 (0.65) CXCR4CYP1A2MAOAMAOBFABP1
SCHEMBL1244338 0.83 MAOA (0.70) CYP1A2MAOAMAOBNPC1RAB9A
SCHEMBL29351380 0.81 CXCR4 (1.00) CXCR4CYP1A2FABP1FABP6NPC1
SCHEMBL589266 0.81 CXCR4 (1.00) CXCR4CYP1A2FABP1FABP6NPC1
SCHEMBL29846220 0.81 MAOA (0.68) CYP1A2MAOAMAOBNPC1RAB9A
SCHEMBL23938004 0.81 NPC1 (0.62) CXCR4CYP1A2MAOAMAOBFABP1
SCHEMBL4777942 0.81 MAOA (0.53) CXCR4CYP1A2MAOAMAOBFABP1
SCHEMBL15830499 0.81 NOS2 (0.67) CYP1A2MAOAMAOBNPC1RAB9A
SCHEMBL1108639 0.81 NPC1 (0.62) CXCR4CYP1A2MAOAMAOBNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116606292-A Pyrido [1,2-a ] pyrimidinone derivatives containing sulfonamide unit, preparation method and application thereof 贵州大学 2023-08-18 CN disclosed