Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | PRKCI | P41743 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 2/20 | 0.36 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.36 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | PNP | P00491 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2190488 | 1.00 | ALDH1A1 (0.48) | ALDH1A1PRKCIKDM4EMAPTRAD52 | |
| SCHEMBL3229989 | 0.76 | KDM4E (0.50) | ALDH1A1KDM4EMAPTAPEX1RECQL | |
| SCHEMBL8367003 | 0.74 | KDM4E (0.39) | ALDH1A1KDM4EMAPTAPEX1RECQL | |
| SCHEMBL620396 | 0.74 | SMN1; SMN2 (0.48) | ALDH1A1KDM4EMAPTTDP1LMNA | |
| SCHEMBL29623085 | 0.74 | KDM4E (0.39) | ALDH1A1KDM4EMAPTAPEX1RECQL | |
| SCHEMBL324999 | 0.74 | ALDH1A1 (0.39) | ALDH1A1KDM4EMAPTAPEX1RECQL | |
| SCHEMBL8044760 | 0.74 | ALDH1A1 (0.39) | ALDH1A1PRKCIKDM4EMAPTRAD52 | |
| SCHEMBL324998 | 0.74 | ALDH1A1 (0.39) | ALDH1A1KDM4EMAPTAPEX1RECQL | |
| SCHEMBL21906548 | 0.74 | ALDH1A1 (0.39) | ALDH1A1KDM4EMAPTAPEX1RECQL | |
| SCHEMBL27796456 | 0.74 | ALDH1A1 (0.39) | ALDH1A1PRKCIKDM4EMAPTRAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111757883-B | Novel inhibitors of bacterial glutaminyl cyclase for the treatment of periodontal disease and related diseases | 弗劳恩霍夫应用研究促进协会 | 2024-02-13 | — | — | CN | disclosed |