SCHEMBL30773786

SCHEMBL30773786

CC[C@@H](C)[C@@H](NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@H](NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](C)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCSC)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](N)Cc1c[nH]c2ccccc12)[C@H](C)CC)C(C)C)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(N)=O

nearest known ligand 0.68

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ NPBWR1 P48145 16/20 0.68
▸ RXFP1 Q9HBX9 1/20 0.66
▸ CCKBR P32239 1/20 0.66
▸ GLP1R P43220 1/20 0.66
▸ PTH1R Q03431 1/20 0.64
▸ IL23R Q5VWK5 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30773852 0.98 NPBWR1 (0.69) NPBWR1RXFP1CCKBRGLP1RPTH1R
SCHEMBL29669569 0.98 NPBWR1 (0.66) NPBWR1RXFP1CCKBRGLP1RPTH1R
SCHEMBL29669608 0.97 NPBWR1 (0.65) NPBWR1RXFP1CCKBRGLP1RPTH1R
SCHEMBL29669637 0.96 NPBWR1 (0.71) NPBWR1
SCHEMBL30773849 0.95 NPBWR1 (0.67) NPBWR1RXFP1CCKBRGLP1RPTH1R
SCHEMBL29669568 0.95 NPBWR1 (0.66) NPBWR1RXFP1CCKBRGLP1RPTH1R
SCHEMBL29669735 0.94 RXFP1 (0.64) NPBWR1RXFP1CCKBRGLP1RPTH1R
SCHEMBL29669730 0.92 NPBWR1 (0.64) NPBWR1RXFP1CCKBRGLP1RPTH1R
SCHEMBL31182496 0.91 GLP1R (0.68) RXFP1CCKBRGLP1RPTH1RIL23R
SCHEMBL30130562 0.88 KISS1R (0.62) NPBWR1GLP1RIL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114641486-B For reducing CB1Peptide compounds for side effects of receptor agonists 庞培法布拉大学 2025-04-01 — — CN claimed
US-12459973-B2 Peptide compounds for reducing side effects of CB1 receptor agonists UNIVERSITAT DE BARCELONA (ES) 2025-11-04 — — US disclosed
CN-114641486-B For reducing CB1Peptide compounds for side effects of receptor agonists 庞培法布拉大学 2025-04-01 — — CN disclosed
US-20240059737-A1 PEPTIDE COMPOUNDS FOR REDUCING SIDE EFFECTS OF CB1 RECEPTOR AGONISTS UNIVERSITAT POMPEU FABRA (ES) 2024-02-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12459973-B2 Peptide compounds for reducing side effects of CB1 receptor agonists CNR2, CNR1, OPRD1 NPBWR1 51/4885RXFP1 53/4885CCKBR 12/4885
US-20240059737-A1 PEPTIDE COMPOUNDS FOR REDUCING SIDE EFFECTS OF CB1 RECEPTOR AGONISTS CNR2, CNR1, OPRD1 NPBWR1 53/4885RXFP1 49/4885CCKBR 14/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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