Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | SLC27A1 | Q6PCB7 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1898074 | 1.00 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2NPC1SLC27A1TSHR | |
| SCHEMBL18559288 | 0.75 | ALDH1A1 (0.67) | ALDH1A1TSHRPOLBKMT2AMAPT | |
| SCHEMBL15835217 | 0.74 | RAB9A (0.51) | ALDH1A1SMN1; SMN2NPC1POLBKMT2A | |
| SCHEMBL18559353 | 0.70 | SMN1; SMN2 (1.00) | ALDH1A1SMN1; SMN2TSHRPOLBKMT2A | |
| SCHEMBL18559194 | 0.70 | TSHR (0.81) | ALDH1A1SMN1; SMN2NPC1TSHRPOLB | |
| SCHEMBL13831536 | 0.69 | MAPT (0.79) | ALDH1A1SMN1; SMN2NPC1SLC27A1POLB | |
| SCHEMBL4196991 | 0.69 | TSHR (0.62) | ALDH1A1TSHRPOLBKMT2AMAPT | |
| SCHEMBL1896673 | 0.69 | SMN1; SMN2 (0.64) | ALDH1A1SMN1; SMN2SLC27A1TSHRKMT2A | |
| SCHEMBL15986422 | 0.69 | MAPT (1.00) | ALDH1A1SMN1; SMN2TSHRPOLBKMT2A | |
| SCHEMBL29354709 | 0.68 | ALDH1A1 (0.76) | ALDH1A1SMN1; SMN2NPC1TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024037910-A1 | SYK INHIBITORS FOR USE IN THE TREATMENT OF CANCER | Institut National de la Santé et de la Recherche Médicale (FR) | 2024-02-22 | — | — | WO | disclosed |