Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SLC27A1 | Q6PCB7 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15835212 | 0.88 | ALDH1A1 (0.52) | SMN1; SMN2MAPTALDH1A1TSHRKDM4E | |
| SCHEMBL16500319 | 0.80 | PTGES (0.54) | SMN1; SMN2MAPTALDH1A1GLAHTT | |
| SCHEMBL18559353 | 0.78 | SMN1; SMN2 (1.00) | SMN1; SMN2MAPTALDH1A1TSHRKDM4E | |
| SCHEMBL17131975 | 0.75 | HTT (0.53) | SMN1; SMN2MAPTTSHRKDM4EHTT | |
| SCHEMBL17131918 | 0.73 | KDM4E (0.50) | SMN1; SMN2MAPTTSHRKDM4EHTT | |
| SCHEMBL14970814 | 0.72 | SMN1; SMN2 (0.71) | SMN1; SMN2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL14970841 | 0.71 | THRB (0.68) | SMN1; SMN2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL18559233 | 0.69 | MAPT (1.00) | MAPTALDH1A1TSHRHSD17B10GAA | |
| SCHEMBL18559263 | 0.69 | MAPT (1.00) | SMN1; SMN2MAPTALDH1A1TSHRMEN1 | |
| SCHEMBL30774051 | 0.69 | ALDH1A1 (0.68) | SMN1; SMN2MAPTALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110112098-A1 | MOLECULES INHIBITING A METABOLIC PATHWAY INVOLVING THE SYK PROTEIN TYROSINE KINASE AND METHOD FOR IDENTIFYING SAID MOLECULES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2011-05-12 | — | — | US | disclosed |
| US-20110112098-A1 | MOLECULES INHIBITING A METABOLIC PATHWAY INVOLVING THE SYK PROTEIN TYROSINE KINASE AND METHOD FOR IDENTIFYING SAID MOLECULES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2011-05-12 | — | — | US | disclosed |
| US-20110112098-A1 | MOLECULES INHIBITING A METABOLIC PATHWAY INVOLVING THE SYK PROTEIN TYROSINE KINASE AND METHOD FOR IDENTIFYING SAID MOLECULES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2011-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110112098-A1 | MOLECULES INHIBITING A METABOLIC PATHWAY INVOLVING THE SYK PROTEIN TYROSINE KINASE AND METHOD FOR IDENTIFYING SAID MOLECULES | SYK, BTK, TYRO3 | SMN1; SMN2 4810/4885MAPT 4486/4885ALDH1A1 3595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.