SCHEMBL30774529

SCHEMBL30774529

N#Cc1ccc(-c2cncc3c2CCN3C(=O)Cc2ccc(C(F)(F)F)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ RIPK1 Q13546 1/20 0.44
▸ STAT3 P40763 1/20 0.42
▸ CYP11B2 P19099 12/20 0.42
▸ ROCK1 Q13464 1/20 0.42
▸ CYP11B1 P15538 11/20 0.42
▸ UCHL1 P09936 1/20 0.40
▸ USP30 Q70CQ3 1/20 0.40
▸ VNN1 O95497 1/20 0.40
▸ KIF11 P52732 1/20 0.40
▸ PANK3 Q9H999 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30774527 0.90 CYP11B2 (0.44) CYP11B2CYP11B1UCHL1USP30
SCHEMBL30774488 0.89 RIPK1 (0.48) RIPK1CYP11B2ROCK1CYP11B1UCHL1
SCHEMBL30774574 0.88 CYP11B2 (0.44) CYP11B2CYP11B1UCHL1USP30
SCHEMBL30774510 0.88 CYP11B2 (0.44) RIPK1CYP11B2CYP11B1UCHL1USP30
SCHEMBL30774460 0.88 CYP11B2 (0.44) RIPK1CYP11B2CYP11B1UCHL1USP30
SCHEMBL30774348 0.86 SMN1; SMN2 (0.49) CYP11B2CYP11B1UCHL1USP30
SCHEMBL30774594 0.85 STAT3 (0.42) RIPK1STAT3ROCK1VNN1KIF11
SCHEMBL30774411 0.85 KDM1A (0.47) STAT3CYP11B2CYP11B1UCHL1USP30
SCHEMBL30774465 0.81 CYP11B2 (0.46) CYP11B2CYP11B1UCHL1USP30
SCHEMBL30774477 0.81 EIF2AK3 (0.43) CYP11B2CYP11B1UCHL1USP30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 — — US claimed
EP-4574830-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Guangzhou Vinnocent Pharmaceutical Limited (CN) 2025-06-25 — — EP claimed
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 — — US disclosed
EP-4574830-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Guangzhou Vinnocent Pharmaceutical Limited (CN) 2025-06-25 — — EP disclosed
WO-2024061371-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF 广州威诺森医药科技有限公司 2024-03-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof STS, NR5A1, CYP21A2 RIPK1 3331/4885STAT3 3957/4885CYP11B2 38/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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