SCHEMBL30774527

SCHEMBL30774527

N#Cc1ccc(-c2cncc3c2CCN3C(=O)Cc2ccc(F)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ CYP11B2 P19099 13/20 0.44
▸ CYP11B1 P15538 9/20 0.43
▸ EIF2AK3 Q9NZJ5 1/20 0.42
▸ UCHL1 P09936 1/20 0.41
▸ USP30 Q70CQ3 1/20 0.41
▸ SLC22A12 Q96S37 1/20 0.39
▸ RORC P51449 1/20 0.39
▸ FPR1 P21462 2/20 0.38
▸ FPR2 P25090 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30774529 0.90 RIPK1 (0.44) CYP11B2CYP11B1UCHL1USP30
SCHEMBL30774574 0.90 CYP11B2 (0.44) CYP11B2CYP11B1EIF2AK3UCHL1USP30
SCHEMBL30774510 0.90 CYP11B2 (0.44) CYP11B2CYP11B1UCHL1USP30SLC22A12
SCHEMBL30774460 0.90 CYP11B2 (0.44) CYP11B2CYP11B1UCHL1USP30SLC22A12
SCHEMBL30774348 0.87 SMN1; SMN2 (0.49) CYP11B2CYP11B1UCHL1USP30
SCHEMBL30774426 0.85 CYP11B2 (0.48) CYP11B2CYP11B1UCHL1USP30SLC22A12
SCHEMBL30774477 0.84 EIF2AK3 (0.43) CYP11B2CYP11B1EIF2AK3UCHL1USP30
SCHEMBL30773967 0.83 NAAA (0.40) CYP11B2CYP11B1EIF2AK3SLC22A12
SCHEMBL30774465 0.83 CYP11B2 (0.46) CYP11B2CYP11B1UCHL1USP30
SCHEMBL30774383 0.83 RIPK1 (0.46) CYP11B2CYP11B1EIF2AK3UCHL1USP30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 — — US claimed
EP-4574830-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Guangzhou Vinnocent Pharmaceutical Limited (CN) 2025-06-25 — — EP claimed
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 — — US disclosed
EP-4574830-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Guangzhou Vinnocent Pharmaceutical Limited (CN) 2025-06-25 — — EP disclosed
WO-2024061371-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF 广州威诺森医药科技有限公司 2024-03-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof STS, NR5A1, CYP21A2 CYP11B2 38/4885CYP11B1 23/4885EIF2AK3 1947/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback