SCHEMBL30774561

SCHEMBL30774561

N#Cc1ccc(-c2cncc3c2OCCN3C(=O)N2CC(Cc3cccc(F)c3)C2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 1/20 0.39
▸ UCHL1 P09936 2/20 0.36
▸ USP30 Q70CQ3 2/20 0.36
▸ CCR3 P51677 1/20 0.36
▸ NAAA Q02083 1/20 0.34
▸ NTRK1 P04629 2/20 0.34
▸ NTRK3 Q16288 2/20 0.34
▸ NTRK2 Q16620 2/20 0.34
▸ CYP11B1 P15538 1/20 0.34
▸ CYP11B2 P19099 1/20 0.34
▸ RIPK1 Q13546 2/20 0.33
▸ CYP3A4 P08684 2/20 0.33
▸ ROCK2 O75116 1/20 0.33
▸ ROCK1 Q13464 1/20 0.33
▸ KDM1A O60341 1/20 0.33
▸ USP2 O75604 1/20 0.33
▸ CYP2D6 P10635 1/20 0.33
▸ BCL2A1 Q16548 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30773988 0.84 NAAA (0.40) UCHL1USP30NAAANTRK1NTRK3
SCHEMBL30774400 0.84 CYP3A4 (0.45) CYP11B1CYP11B2CYP3A4USP2CYP2D6
SCHEMBL30774590 0.83 USP30 (0.42) UCHL1USP30CYP11B1CYP11B2CYP3A4
SCHEMBL30773960 0.83 NAAA (0.46) UCHL1USP30NAAANTRK1NTRK3
SCHEMBL30774644 0.81 USP30 (0.46) UCHL1USP30CCR3KDM1AALDH1A1
SCHEMBL30774398 0.81 USP30 (0.46) UCHL1USP30CCR3KDM1AALDH1A1
SCHEMBL30774894 0.80 CYP3A4 (0.42) MAPTUCHL1USP30NAAACYP11B1
SCHEMBL31635534 0.79 USP30 (0.42) UCHL1USP30CYP11B1CYP11B2CYP3A4
SCHEMBL31635537 0.79 USP30 (0.43) MAPTUCHL1USP30NTRK1NTRK3
SCHEMBL30774439 0.77 CHRM1 (0.46) UCHL1USP30CYP11B1CYP11B2PAX8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 — — US claimed
EP-4574830-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Guangzhou Vinnocent Pharmaceutical Limited (CN) 2025-06-25 — — EP claimed
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 — — US disclosed
EP-4574830-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Guangzhou Vinnocent Pharmaceutical Limited (CN) 2025-06-25 — — EP disclosed
WO-2024061371-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF 广州威诺森医药科技有限公司 2024-03-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof STS, NR5A1, CYP21A2 MAPT 4813/4885UCHL1 1728/4885USP30 728/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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