SCHEMBL30773988

SCHEMBL30773988

N#Cc1ccc(-c2cncc3c2OCCN3C(=O)Cc2cccc(F)c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ NAAA Q02083 4/20 0.40
▸ FAAH O00519 3/20 0.40
▸ RIPK1 Q13546 3/20 0.40
▸ EIF2AK3 Q9NZJ5 1/20 0.40
▸ SLC22A12 Q96S37 2/20 0.38
▸ NTRK1 P04629 1/20 0.37
▸ NTRK3 Q16288 1/20 0.37
▸ NTRK2 Q16620 1/20 0.37
▸ GRM5 P41594 1/20 0.37
▸ CYP11B1 P15538 2/20 0.37
▸ CYP11B2 P19099 2/20 0.37
▸ UCHL1 P09936 1/20 0.36
▸ USP30 Q70CQ3 1/20 0.36
▸ USP2 O75604 1/20 0.35
▸ CYP3A4 P08684 1/20 0.35
▸ CYP2D6 P10635 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30773960 0.91 NAAA (0.46) NAAASLC22A12NTRK1NTRK3NTRK2
SCHEMBL30773980 0.90 RIPK1 (0.41) NAAAFAAHRIPK1EIF2AK3SLC22A12
SCHEMBL30774028 0.90 NAAA (0.40) NAAAFAAHRIPK1EIF2AK3SLC22A12
SCHEMBL30773967 0.89 NAAA (0.40) NAAAFAAHEIF2AK3SLC22A12CYP11B1
SCHEMBL30774563 0.89 GPR142 (0.46) NAAAFAAHRIPK1EIF2AK3SLC22A12
SCHEMBL30773978 0.87 FAAH (0.43) NAAAFAAHRIPK1EIF2AK3
SCHEMBL30774590 0.85 USP30 (0.42) CYP11B1CYP11B2UCHL1USP30USP2
SCHEMBL30774894 0.85 CYP3A4 (0.42) NAAAFAAHSLC22A12CYP11B1CYP11B2
SCHEMBL30774026 0.84 NAAA (0.40) NAAAFAAHEIF2AK3SLC22A12CYP11B1
SCHEMBL30773965 0.84 FAAH (0.40) NAAAFAAHRIPK1SLC22A12CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 — — US claimed
EP-4574830-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Guangzhou Vinnocent Pharmaceutical Limited (CN) 2025-06-25 — — EP claimed
WO-2024061371-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF 广州威诺森医药科技有限公司 2024-03-28 — — WO claimed
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 — — US disclosed
EP-4574830-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Guangzhou Vinnocent Pharmaceutical Limited (CN) 2025-06-25 — — EP disclosed
WO-2024061371-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF 广州威诺森医药科技有限公司 2024-03-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof STS, NR5A1, CYP21A2 NAAA 1168/4885FAAH 1677/4885RIPK1 3331/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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