SCHEMBL30774832

SCHEMBL30774832

N#Cc1ccc(-c2cncc3c2OCCN3C(=O)C2CN(Cc3ccc(F)cc3)C2)cc1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ PRKAA2 P54646 12/20 0.41
▸ USP30 Q70CQ3 1/20 0.40
▸ PRKAB2 O43741 5/20 0.40
▸ PRKAG1 P54619 5/20 0.40
▸ PRKAA1 Q13131 5/20 0.40
▸ PRKAG3 Q9UGI9 5/20 0.40
▸ PRKAG2 Q9UGJ0 5/20 0.40
▸ PRKAB1 Q9Y478 5/20 0.40
▸ CYP11B1 P15538 1/20 0.40
▸ CYP11B2 P19099 1/20 0.40
▸ DRD2 P14416 3/20 0.39
▸ DRD3 P35462 3/20 0.39
▸ S1PR5 Q9H228 1/20 0.39
▸ DPP4 P27487 1/20 0.38
▸ DPP8 Q6V1X1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30774354 0.96 USP30 (0.43) PRKAA2USP30S1PR5DPP4DPP8
SCHEMBL30774590 0.90 USP30 (0.42) USP30CYP11B1CYP11B2
SCHEMBL30774349 0.89 PRKAB2 (0.42) PRKAA2USP30PRKAB2PRKAG1PRKAA1
SCHEMBL30774840 0.87 ROCK2 (0.44) USP30DRD2DRD3
SCHEMBL30774432 0.87 USP30 (0.42) USP30CYP11B2
SCHEMBL30774559 0.85 USP30 (0.41) PRKAA2USP30PRKAB2PRKAG1PRKAA1
SCHEMBL30774644 0.85 USP30 (0.46) USP30
SCHEMBL30774398 0.85 USP30 (0.46) USP30
SCHEMBL30773967 0.84 NAAA (0.40) PRKAA2CYP11B1CYP11B2DRD2
SCHEMBL30774542 0.84 USP30 (0.40) PRKAA2USP30PRKAB2PRKAG1PRKAA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 — — US claimed
EP-4574830-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Guangzhou Vinnocent Pharmaceutical Limited (CN) 2025-06-25 — — EP claimed
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 — — US disclosed
EP-4574830-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Guangzhou Vinnocent Pharmaceutical Limited (CN) 2025-06-25 — — EP disclosed
WO-2024061371-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF 广州威诺森医药科技有限公司 2024-03-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof STS, NR5A1, CYP21A2 PRKAA2 1880/4885USP30 728/4885PRKAB2 3584/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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