Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 9/20 | 0.64 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.64 |
| ▸ | KMO | O15229 | 1/20 | 0.62 |
| ▸ | KDM5C | P41229 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | KDM6B | O15054 | 3/20 | 0.57 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.57 |
| ▸ | KDM3A | Q9Y4C1 | 3/20 | 0.57 |
| ▸ | KDM5B | Q9UGL1 | 7/20 | 0.56 |
| ▸ | KDM4A | O75164 | 5/20 | 0.56 |
| ▸ | KDM5A | P29375 | 4/20 | 0.56 |
| ▸ | KDM4B | O94953 | 2/20 | 0.55 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.54 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.54 |
| ▸ | CTRC | Q99895 | 1/20 | 0.54 |
| ▸ | KDM1A | O60341 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitrous Acid SCHEMBL29134645 | 0.94 | KDM4C (0.59) | KDM4CKDM2BKMOKDM5CKDM4E | |
| SCHEMBL4894953 | 0.85 | LOXL2 (0.56) | KDM4CKDM2BKMOKDM4EKDM5B | |
| SCHEMBL4895581 | 0.85 | LOXL2 (0.56) | KDM4CKDM2BKMOKDM4EKDM5B | |
| SCHEMBL2556149 | 0.85 | KMO (0.60) | KDM4CKDM2BKMOKDM5CKDM4E | |
| SCHEMBL29932995 | 0.85 | MAP4K4 (0.54) | KDM4CKDM2BKMOKDM5CKDM5B | |
| SCHEMBL29541336 | 0.84 | KDM4C (0.71) | KDM4CKMOKDM5CKDM4EKDM6B | |
| SCHEMBL648273 | 0.84 | KDM4C (0.71) | KDM4CKMOKDM5CKDM4EKDM6B | |
| SCHEMBL23303939 | 0.83 | KMO (0.67) | KDM4CKDM2BKMOKDM5CKDM4E | |
| SCHEMBL30318846 | 0.83 | KMO (0.67) | KDM4CKDM2BKMOKDM5CKDM4E | |
| SCHEMBL19433797 | 0.83 | LOXL2 (0.60) | KDM4CKDM2BKMOKDM4EKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727549-A2 | PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS | University of Georgia Research Foundation, Inc. (US) | 2026-04-22 | — | — | EP | disclosed |
| US-20260097046-A1 | PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS | UNIV GEORGIA (US) | 2026-04-09 | — | — | US | disclosed |
| WO-2024258900-A2 | PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2024-12-19 | — | — | WO | disclosed |
| CN-117343002-A | Synthesis method of beta-cyanoalkyl pyridine compound | 西南医科大学 | 2024-01-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260097046-A1 | PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS | SUB1, PFN1, HCCS | KDM4C 2754/4885KDM2B 3244/4885KMO 2781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.