Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 1/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.39 |
| ▸ | KRAS | P01116 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 3/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.37 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.37 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 2/20 | 0.35 |
| ▸ | IDH2 | P48735 | 1/20 | 0.35 |
| ▸ | WNT1 | P04628 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31365779 | 1.00 | OXTR (0.39) | OXTRAVPR1AKRASSTSGPR119 | |
| SCHEMBL30775991 | 1.00 | OXTR (0.39) | OXTRAVPR1AKRASSTSGPR119 | |
| SCHEMBL30776008 | 0.83 | KRAS (0.42) | OXTRAVPR1AKRASSTSGPR119 | |
| SCHEMBL25324549 | 0.83 | STS (0.38) | OXTRAVPR1AKRASSTSGPR119 | |
| SCHEMBL31365790 | 0.82 | P2RX3 (0.40) | KRASSTSGPR119EHMT2IDH1 | |
| SCHEMBL25326740 | 0.82 | P2RX3 (0.40) | KRASSTSGPR119EHMT2IDH1 | |
| SCHEMBL30395790 | 0.80 | GPR119 (0.45) | OXTRAVPR1AKRASGPR119 | |
| SCHEMBL25255551 | 0.80 | GPR119 (0.45) | OXTRAVPR1AKRASGPR119 | |
| SCHEMBL25254057 | 0.80 | GPR119 (0.41) | OXTRAVPR1AKRASGPR119RORC | |
| SCHEMBL31365782 | 0.80 | GPR119 (0.41) | OXTRAVPR1AKRASGPR119RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568972-A1 | NEW HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024033277-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2024-02-15 | — | — | WO | disclosed |